NBPF6 polyclonal antibody

Members of the neuroblastoma breakpoint family are encoded by genes that map to a region of segmental duplications on human chromosome 1. Both NBPF4 (neuroblastoma breakpoint family member 4) and NBPF6 (neuroblastoma breakpoint family member 6) are cytoplasmic proteins that belong to the NBPF family. NBPF4 contains 123 amino acids and is expressed in testis,while NBPF6 consists of 638 amino acids and contains 3 NBPF domains. Like other NBPF family members, both proteins are encoded by genes that map to human chromosome 1p13.3. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome,Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.