TPRA1 polyclonal antibody

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR175 (G protein-coupled receptor 175), also known as TPRA40 or PP6566, is a 373 amino acid multi-pass membrane protein that is ubiquitously expressed and functions as a G-protein coupled receptor. The gene encoding GPR175 maps to human chromosome 3 and is expressed as multiple alternatively spliced isoforms.