PHF11 polyclonal antibody

PHF11 (PHD Finger Protein 11A), also known as Phf11a, is a 293 amino acid member of the PHD finger protein family. Members of the PHD finger protein family function as transcriptional regulators that affect gene expression by modulating chromatin structure. With a subcellular localization to the nucleus, PHF11 is expressed in heart, kidney, liver spleen, testis and ureter tissues. PFH11 contains one PHD-type zinc finger domain. PHF11 is thought to interact with HDAC9. It is also thought that PHF11 may be involved in the immune response through regulation of T cell activities in humans, and may operate as a Th1 cell regulator in immune responses in mice. The PHF11 gene is conserved in human, chimpanzee, canine, bovine, rat, and chicken.