SIK2 polyclonal antibody

QIK (Qin-induced kinase) is a serine/threonine-protein kinase that belongs to the AMPK/SNF1 kinase family. Also designated SIK2 (SNF1-like kinase 2), QIK is one of twelve human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK) related to AMPK. QIK is a ubiquitously expressed protein and is rapidly upregulated after a hormone-regulated form of Qin is activated. In vitro kinase tests demonstrate that QIK is capable of autophosphorylation. Elevated levels of QIK transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets.