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Dima Biotech

SKU(재고 관리 코드):BME100032

Anti-TNFRSF10B (tigatuzumab biosimilar) mAb

Anti-TNFRSF10B (tigatuzumab biosimilar) mAb

Size
Target
Uniprot-id
PRODUCT DATA
COMMON NAME

GEN-1029, HexaBody-DR5/DR5, Hx-DR5-01/05

SYNONYMS

TNFRSF10B;RAILR2;RAIL-R2;D262;R5;ILLER;RICK2;TNFR9;RICKB

APPLICATIONS

ELISA

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

HOST SPECIES

Humanized

IGG TYPE

IgG1

REACTIVITY

Human

TARGET

UNIPROT ID

O14763

DESCRIPTION

Anti-TNFRSF10B (tigatuzumab biosimilar) mAb

DELIVERY

In Stock

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.

USAGE

Research use only

IMAGES

Elisa-BME100032 Anti TNFRSF10B tigatuzumab biosimilar mAb Elisa fig1

Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TNFRSF10B, mFc tagged protein (PME100465) can bind Anti-TNFRSF10B  Neutralizing antibody in a linear range of 3.2-80 ng/ml.

FC-BME100032 Anti TNFRSF10B mAbtigatuzumab biosimilar FLOW Fig2

Figure 2. TNFRSF10B protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-TNFRSF10B (tigatuzumab) on Expi293 cells transfected with human TNFRSF10B(Blue histogram)or Expi293 transfected with irrelevant protein(Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein(Orange histogram)

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