| TARGET | |
|---|---|
| SYNONYMS |
TNFRSF4; OX40; CD134; OX40L receptor; ACT35; TXGP1L |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-OX40 antibody(DM116); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P43489 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1:BCL2-XL; and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4 T cell response; as well as in T cell-dependent B cell proliferation and differentiation. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100116
Anti-OX40 antibody(DM116), Rabbit mAb
Anti-OX40 antibody(DM116), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human OX40 protein, hFc-His tagged protein (PME100022) can bind Rabbit anti-OX40 monoclonal antibody (clone: DM116) in a linear range of 6-70 ng/ml.
Figure 2. Flow cytometry analysis with Anti-OX40 (DM116) on Expi293 cells transfected with human OX40 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram).
