| TARGET | |
|---|---|
| SYNONYMS |
CD217;CDw217;IL-17RA;IL17R;CANDF5;hIL-17R |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-IL17RA antibody(DM126); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q96F46 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100126
Anti-IL17RA antibody(DM126), Rabbit mAb
Anti-IL17RA antibody(DM126), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human IL-17RA protein, His tagged protein (PME100468) can bind Rabbit anti-IL-17RA monoclonal antibody (clone: DM126) in a linear range of 0. 3-15 ng/ml.
Figure 2. Flow cytometry analysis with Anti-IL-17RA (DM126) on Expi293 cells transfected with human IL17RA(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
