| TARGET | |
|---|---|
| SYNONYMS |
TNFSF12 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-TNFSF12 antibody(DM141); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
O43508 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14:TWEAKR receptor. This cytokine has overlapping signaling functions with TNF; but displays a much wider tissue distribution. This cytokine; which exists in both membrane-bound and secreted forms; can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells; and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977; TNFSF12-TNFSF13. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100141
Anti-TNFSF12 antibody(DM141), Rabbit mAb
Anti-TNFSF12 antibody(DM141), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human TNFSF12 protein, hFc tagged protein (PME100105) can bind Rabbit anti-TNFSF12 monoclonal antibody(clone: DM141) in a linear range of 0. 1-10 ng/ml.
Figure 2. Flow cytometry analysis with Anti-TNFSF12 (DM141) on Expi293 cells transfected with human TNFSF12 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
