| TARGET | |
|---|---|
| SYNONYMS |
BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-BAFF-R antibody(DM143); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q96RJ3 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100143
Anti-BAFF-R antibody(DM143), Rabbit mAb
Anti-BAFF-R antibody(DM143), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human BAFFR protein, mFc tagged protein (PME100044) can bind Rabbit anti-BAFFR monoclonal antibody(clone: DM143) in a linear range of 0.8-50
Figure 2. Flow cytometry analysis with Anti-BAFFR (DM143) on Expi293 cells transfected with human BAFFR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
