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Dima Biotech

SKU(재고 관리 코드):DME100154

Anti-FAP antibody(DM154), Rabbit mAb

Anti-FAP antibody(DM154), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

FAP;FAPalpha;SIMP;Seprase;APCE

HOST SPECIES

Rabbit

DESCRIPTION

Anti-FAP antibody(DM154); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

Q12884

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers; granulation tissue of healing wounds; and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development; tissue repair; and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

USAGE

Research use only

IMAGES

antibody-DME100154 FAP ELISA Fig1

Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human FAP protein, His tagged protein (PME100626) can bind Rabbit anti-FAP monoclonal antibody(clone: DM154) in a linear range of 1-500 ng/ml.

antibody-DME100154 FAP Flow Fig2

Figure 2. Flow cytometry analysis with Anti-FAP (DM154) on Expi293 cells transfected with human FAP (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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