TARGET | |
---|---|
SYNONYMS |
CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-CD171 antibody(DM155); Rabbit mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P32004 |
IGG TYPE |
Rabbit IgG |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain; consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III); is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development; including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia; retardation; aphasia; spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants; some of which include an alternate exon that is considered to be specific to neurons. |
USAGE |
Research use only |
SKU(재고 관리 코드):DME100155
Anti-CD171 antibody(DM155), Rabbit mAb
Anti-CD171 antibody(DM155), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human CD171 protein, His tagged protein (PME100173) can bind Rabbit anti-CD171 monoclonal antibody(clone: DM155) in a linear range of 1-100 ng/ml.
Figure 2. CD171 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD171 (DM155) on Expi293 cells transfected with human CD171 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).