| TARGET | |
|---|---|
| SYNONYMS |
CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-IL6R antibody(DM152); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P08887 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST:GP130:IL6-beta); a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases; such as multiple myeloma; autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100152
Anti-IL6R antibody(DM152), Rabbit mAb
Anti-IL6R antibody(DM152), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human IL6R protein, His tagged protein (PME100109) can bind Rabbit anti-IL6R monoclonal antibody(clone: DM152) in a linear range of 1-100 ng/ml.
Figure 2. Flow cytometry analysis with Anti-IL-6R (DM152) on Expi293 cells transfected with human IL-6R (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
