| TARGET | |
|---|---|
| SYNONYMS |
ROR1;NTRKR1 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-ROR1 antibody(DM149); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q01973 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Jun 2012] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100149
Anti-ROR1 antibody(DM149), Rabbit mAb
Anti-ROR1 antibody(DM149), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human ROR1 protein, His tagged protein (PME100399) can bind Rabbit anti-ROR1 monoclonal antibody(clone: DM149) in a linear range of 1-50 ng/ml.
Figure 2. ROR1 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-ROR1 (DM149) on Expi293 cells transfected with human ROR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
