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Dima Biotech

SKU(재고 관리 코드):DME100168

Anti-MICB antibody(DM168), Rabbit mAb

Anti-MICB antibody(DM168), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

MIC-B; PERB11.2

HOST SPECIES

Rabbit

DESCRIPTION

Anti-MICB antibody(DM168); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

Q29980

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells; CD8 alphabeta T cells; and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however; it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

USAGE

Research use only

IMAGES

antibody-DME100168 MICB Flow Fig1

Figure 1. MICB protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-MICB (DM168) on Expi293 cells transfected with human MICB (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

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