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Dima Biotech

SKU(재고 관리 코드):DME100170

Anti-LIGHT antibody(DM170), Rabbit mAb

Anti-LIGHT antibody(DM170), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

TNFSF14; CD258; HVEML; LIGHT; LTg

HOST SPECIES

Rabbit

DESCRIPTION

Anti-LIGHT antibody(DM170); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

O43557

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14; which is a member of the tumor necrosis factor receptor superfamily; and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells; and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

USAGE

Research use only

IMAGES

antibody-DME100170 LIGHT Flow Fig1

Figure 1. Flow cytometry analysis with Anti-LIGHT (DM170) on Expi293 cells transfected with human LIGHT (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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