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Dima Biotech

SKU(재고 관리 코드):DME100174

Anti-ROR2 antibody(DM174), Rabbit mAb

Anti-ROR2 antibody(DM174), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

ROR2;NTRKR2

HOST SPECIES

Rabbit

DESCRIPTION

Anti-ROR2 antibody(DM174); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

Q01974

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B; a skeletal disorder characterized by hypoplasia:aplasia of distal phalanges and nails. In addition; mutations in this gene can cause the autosomal recessive form of Robinow syndrome; which is characterized by skeletal dysplasia with generalized limb bone shortening; segmental defects of the spine; brachydactyly; and a dysmorphic facial appearance.

USAGE

Research use only

IMAGES

antibody-DME100174 ROR2 Flow Fig1

Figure 1. ROR2 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-ROR2 (DM174) on Expi293 cells transfected with human ROR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

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