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Dima Biotech

SKU(재고 관리 코드):DME100176

Anti-CD10 antibody(DM176), Rabbit mAb

Anti-CD10 antibody(DM176), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

MME;CALLA;CD10;DKFZp686O16152;MGC126681;MGC126707;NEP;SFE;Neprilysin

HOST SPECIES

Rabbit

DESCRIPTION

Anti-CD10 antibody(DM176); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

P08473

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype; which represent 85% of cases of ALL. This protein is not restricted to leukemic cells; however; and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon; enkephalins; substance P; neurotensin; oxytocin; and bradykinin.

USAGE

Research use only

IMAGES

antibody-DME100176 CD10 Flow Fig1

Figure 1. CD10 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD10 (DM176) on Expi293 cells transfected with human CD10 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

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