TARGET | |
---|---|
SYNONYMS |
CD309; FLK1; VEGFR; VEGFR2 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-VEGFR2 antibody(DM185); Rabbit mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P35968 |
IGG TYPE |
Rabbit IgG |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor; known as kinase insert domain receptor; is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation; survival; migration; tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors; including Rab GTPase; P2Y purine nucleotide receptor; integrin alphaVbeta3; T-cell protein tyrosine phosphatase; etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
USAGE |
Research use only |
SKU(재고 관리 코드):DME100185
Anti-VEGFR2 antibody(DM185), Rabbit mAb
Anti-VEGFR2 antibody(DM185), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-VEGFR2 (DM185) on Expi293 cells transfected with human VEGFR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).