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Dima Biotech

SKU(재고 관리 코드):DME100185

Anti-VEGFR2 antibody(DM185), Rabbit mAb

Anti-VEGFR2 antibody(DM185), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

CD309; FLK1; VEGFR; VEGFR2

HOST SPECIES

Rabbit

DESCRIPTION

Anti-VEGFR2 antibody(DM185); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

P35968

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor; known as kinase insert domain receptor; is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation; survival; migration; tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors; including Rab GTPase; P2Y purine nucleotide receptor; integrin alphaVbeta3; T-cell protein tyrosine phosphatase; etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

USAGE

Research use only

IMAGES

antibody-DME100185 VEGFR2 Flow Fig1

Figure 1. Flow cytometry analysis with Anti-VEGFR2 (DM185) on Expi293 cells transfected with human VEGFR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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