TARGET | |
---|---|
SYNONYMS |
IL-2; lymphokine; TCGF |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-IL2 antibody(DM187); Rabbit mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P60568 |
IGG TYPE |
Rabbit IgG |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4; IL7; IL9; IL15; IL21; erythropoietin; and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4 and CD8 T lymphocytes; that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic; which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease; which suggests an essential role of this gene in the immune response to antigenic stimuli. |
USAGE |
Research use only |
SKU(재고 관리 코드):DME100187
Anti-IL2 antibody(DM187), Rabbit mAb
Anti-IL2 antibody(DM187), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-IL2 (DM187) on Expi293 cells transfected with human IL2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).