| TARGET | |
|---|---|
| SYNONYMS |
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-CD45 antibody(DM193); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P08575 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100193
Anti-CD45 antibody(DM193), Rabbit mAb
Anti-CD45 antibody(DM193), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-CD45 (DM193) on Expi293 cells transfected with human CD45 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
