| TARGET | |
|---|---|
| SYNONYMS |
CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-NEFL(89-400) antibody(DM199); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P07196 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Neurofilaments are type IV intermediate filament heteropolymers composed of light; medium; and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E); disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100199
Anti-NEFL(89-400) antibody(DM199), Rabbit mAb
Anti-NEFL(89-400) antibody(DM199), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human NEFL(89-400) protein, His tagged protein (PME100648) can bind Rabbit anti-NEFL(89-400) monoclonal antibody(clone: DM199) in a linear range of 1-100 ng/ml.
