TARGET | |
---|---|
SYNONYMS |
CSF; GMCSF |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-GM-CSF antibody(DM200); Rabbit mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P04141 |
IGG TYPE |
Rabbit IgG |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene is a cytokine that controls the production; differentiation; and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31; which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4; 5; and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines; including the one produced by this gene; have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq; Aug 2020] |
USAGE |
Research use only |
SKU(재고 관리 코드):DME100200
Anti-GM-CSF antibody(DM200), Rabbit mAb
Anti-GM-CSF antibody(DM200), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-GM-CSF (DM200) on Expi293 cells transfected with human GM-CSF (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).