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Dima Biotech

SKU(재고 관리 코드):DME100206

Anti-IL15RA antibody(DM206), Rabbit mAb

Anti-IL15RA antibody(DM206), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

CD215

HOST SPECIES

Rabbit

DESCRIPTION

Anti-IL15RA antibody(DM206); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

Q13261

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits; IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha; an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA; IL15RA is capable of binding IL15 with high affinity independent of other subunits; which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1:BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

USAGE

Research use only

IMAGES

antibody-DME100206 IL15RA Flow Fig1

Figure 1. Flow cytometry analysis with Anti-IL15RA (DM206) on Expi293 cells transfected with human IL15RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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