TARGET | |
---|---|
SYNONYMS |
CD215 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-IL15RA antibody(DM206); Rabbit mAb |
DELIVERY |
In Stock |
UNIPROT ID |
Q13261 |
IGG TYPE |
Rabbit IgG |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits; IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha; an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA; IL15RA is capable of binding IL15 with high affinity independent of other subunits; which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1:BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. |
USAGE |
Research use only |
SKU(재고 관리 코드):DME100206
Anti-IL15RA antibody(DM206), Rabbit mAb
Anti-IL15RA antibody(DM206), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-IL15RA (DM206) on Expi293 cells transfected with human IL15RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).