| TARGET | |
|---|---|
| SYNONYMS |
CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-CXCR3 antibody(DM208); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P49682 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9:Mig (monokine induced by interferon-g); CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4:PF4 (PMID:12782716). [provided by RefSeq; Jun 2011] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DME100208
Anti-CXCR3 antibody(DM208), Rabbit mAb
Anti-CXCR3 antibody(DM208), Rabbit mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-CXCR3 (DM208) on Expi293 cells transfected with human CXCR3 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
