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Dima Biotech

SKU(재고 관리 코드):DME100210

Anti-DKK1 antibody(DM210), Rabbit mAb

Anti-DKK1 antibody(DM210), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

DKK-1; SK

HOST SPECIES

Rabbit

DESCRIPTION

Anti-DKK1 antibody(DM210); Rabbit mAb

DELIVERY

In Stock

UNIPROT ID

O94907

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation; invasion and growth in cancer cell lines.

USAGE

Research use only

IMAGES

antibody-DME100210 DKK1 Flow Fig1

Figure 1. Flow cytometry analysis with Anti-DKK1 (DM210) on Expi293 cells transfected with human DKK1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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