TARGET | |
---|---|
SYNONYMS |
Interferon alpha:beta receptor 1;IFN-R-1;IFN-alpha:beta receptor 1;CRF2-1;Type I interferon receptor 1 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-IFNAR1 antibody(DMC221); IgG1 Chimeric mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P17181 |
IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases; which in turn phosphorylate several proteins; including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. |
USAGE |
Research use only |
SKU(재고 관리 코드):DMC100221
Anti-IFNAR1 antibody(DMC221), IgG1 Chimeric mAb
Anti-IFNAR1 antibody(DMC221), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-IFNAR1 (DMC221) on Expi293 cells transfected with human IFNAR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).