TARGET | |
---|---|
SYNONYMS |
NECTIN2; HVEB; PRR2; PVRL2; PVRR2 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-CD112 antibody(DMC224); IgG1 Chimeric mAb |
DELIVERY |
In Stock |
UNIPROT ID |
Q92692 |
IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus; and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. |
USAGE |
Research use only |
SKU(재고 관리 코드):DMC100224
Anti-CD112 antibody(DMC224), IgG1 Chimeric mAb
Anti-CD112 antibody(DMC224), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. CD112 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD112 (DMC224) on Expi293 cells transfected with human CD112 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).