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Dima Biotech

DME100028B

Biotinylated Anti-CD38 antibody(DM29), Rabbit mAb

Biotinylated Anti-CD38 antibody(DM29), Rabbit mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

T10; cADPr hydrolase 1
HOST SPECIES

Rabbit
DESCRIPTION

Biotinylated Anti-CD38 antibody(DM29); Rabbit mAb
DELIVERY

2-3 weeks
UNIPROT ID

P28907
IGG TYPE

Rabbit IgG
CLONALITY

Monoclonal
REACTIVITY

Human
APPLICATIONS

ELISA; Flow Cyt
RECOMMENDED DILUTIONS

ELISA 1:5000-10000; Flow Cyt 1:100
PURIFICATION

Purified from cell culture supernatant by affinity chromatography
FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

CD antigen CD38 is also known as ADP-ribosyl cyclase 1; which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses; metabolic disturbances; and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection; leukemias; myelomas; solid tumors; type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
USAGE

Research use only
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