TARGET | |
---|---|
SYNONYMS |
HAVCR2; TIM3; TIMD3; FLJ14428; KIM3 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Biotinylated Anti-TIM3 antibody(DM82); Rabbit mAb |
DELIVERY |
2-3 weeks |
UNIPROT ID |
Q8TDQ0 |
IGG TYPE |
Rabbit IgG |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
ELISA; Flow Cyt |
RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene belongs to the immunoglobulin superfamily; and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions; whereas; Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation; and inhibits Th1-mediated auto- and alloimmune responses; and promotes immunological tolerance. |
USAGE |
Research use only |
SKU(재고 관리 코드):DME100082B