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Dima Biotech

SKU(재고 관리 코드):DMC100269

Anti-CD44 antibody(DMC269), IgG1 Chimeric mAb

Anti-CD44 antibody(DMC269), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

CD44;CDW44;CSPG8;ECMR-III;HCELL;HUTCH-I;IN;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;Epican

HOST SPECIES

Rabbit

DESCRIPTION

Anti-CD44 antibody(DMC269); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

P16070

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions; cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands; such as osteopontin; collagens; and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation; recirculation and homing; hematopoiesis; and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms; however; the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein; and may be related to tumor metastasis.

USAGE

Research use only

IMAGES

antibody-DMC100269 CD44 Flow Fig1

Figure 1. Flow cytometry analysis with Anti-CD44 (DMC269) on Expi293 cells transfected with human CD44 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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