| TARGET | |
|---|---|
| SYNONYMS |
IL-5;TRF;Interleukin-5;EDF |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-IL5 antibody(DMC274); IgG1 Chimeric mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P05113 |
| IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
Flow Cyt |
| RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation; maturation; recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor; which is a heterodimer; whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2:GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4); interleukin 13 (IL13); and CSF2 . This gene; IL4; and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DMC100274
Anti-IL5 antibody(DMC274), IgG1 Chimeric mAb
Anti-IL5 antibody(DMC274), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-IL5 (DMC274) on Expi293 cells transfected with human IL5 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
