TARGET | |
---|---|
SYNONYMS |
AFPD; FETA; HPAFP |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-AFP antibody(DMC281); IgG1 Chimeric mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P02771 |
IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
Flow Cyt |
RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes alpha-fetoprotein; a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma; and has prognostic value for managing advanced gastric cancer. However; hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin; and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms; and binds copper; nickel; fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
USAGE |
Research use only |
SKU(재고 관리 코드):DMC100281
Anti-AFP antibody(DMC281), IgG1 Chimeric mAb
Anti-AFP antibody(DMC281), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-AFP (DMC281) on Expi293 cells transfected with human AFP (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).