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Dima Biotech

SKU(재고 관리 코드):DMC100282

Anti-IL11RA antibody(DMC282), IgG1 Chimeric mAb

Anti-IL11RA antibody(DMC282), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

IL-11 R alpha;IL-11 RA;IL11RA;Interleukin-11 receptor subunit alpha;IL-11 receptor subunit alpha;IL-11R subunit alpha;IL-11R-alpha

HOST SPECIES

Rabbit

DESCRIPTION

Anti-IL11RA antibody(DMC282); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

Q14626

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor; which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor; since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

USAGE

Research use only

IMAGES

antibody-DMC100282 IL11RA Flow Fig1

Figure 1. IL11RA protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-IL11RA (DMC282) on Expi293 cells transfected with human IL11RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

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