TARGET | |
---|---|
SYNONYMS |
BETA-HFR; FBP; FBP:PL-1; FOLR1; FR-BETA; FR-P3; FRbeta |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P14207 |
IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
Flow Cyt |
RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene is a member of the folate receptor (FOLR) family; and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives; and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins; respectively. Although this protein was originally thought to be specific to placenta; it can also exist in other tissues; and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. |
USAGE |
Research use only |
SKU(재고 관리 코드):DMC100390
Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb
Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-FOLR2 (DMC390) on Expi293 cells transfected with human FOLR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).