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Dima Biotech

SKU(재고 관리 코드):DMC100390

Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb

Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

BETA-HFR; FBP; FBP:PL-1; FOLR1; FR-BETA; FR-P3; FRbeta

HOST SPECIES

Rabbit

DESCRIPTION

Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

P14207

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the folate receptor (FOLR) family; and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives; and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins; respectively. Although this protein was originally thought to be specific to placenta; it can also exist in other tissues; and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

USAGE

Research use only

IMAGES

antibody-DMC100390 FOLR2 Flow Fig1

Figure 1. Flow cytometry analysis with Anti-FOLR2 (DMC390) on Expi293 cells transfected with human FOLR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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