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Dima Biotech

SKU(재고 관리 코드):DMC100391

Anti-FOLR1 antibody(DMC391), IgG1 Chimeric mAb

Anti-FOLR1 antibody(DMC391), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

FBP; FOLR; FRalpha

HOST SPECIES

Rabbit

DESCRIPTION

Anti-FOLR1 antibody(DMC391); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

P15328

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives; and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters; multiple transcription start sites; and alternative splicing; multiple transcript variants encoding the same protein have been found for this gene.

USAGE

Research use only

IMAGES

antibody-DMC100391 FOLR1 Flow Fig1

Figure 1. FOLR1 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-FOLR1 (DMC391) on Expi293 cells transfected with human FOLR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

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