| TARGET | |
|---|---|
| SYNONYMS |
D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-PMEL antibody(DMC420); IgG1 Chimeric mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P40967 |
| IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
Flow Cyt |
| RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes; which are the melanin-producing organelles in melanocytes; and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):DMC100420
Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb
Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-PMEL (DMC420) on Expi293 cells transfected with human PMEL (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
