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Dima Biotech

SKU(재고 관리 코드):DMC100422

Anti-IGFBP7 antibody(DMC422), IgG1 Chimeric mAb

Anti-IGFBP7 antibody(DMC422), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

IBP-7; TAF; IGFBP-rP1; MAC25 protein

HOST SPECIES

Rabbit

DESCRIPTION

Anti-IGFBP7 antibody(DMC422); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

Q16270

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

USAGE

Research use only

IMAGES

antibody-DMC100422 IGFBP7 Flow Fig1

Figure 1. Flow cytometry analysis with Anti-IGFBP7 (DMC422) on Expi293 cells transfected with human IGFBP7 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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