TARGET | |
---|---|
SYNONYMS |
CD63 antigen;Granulophysin;LAMP-3;Limp1;Melanoma-associated antigen ME491;OMA81H;Ocular melanoma-associated antigen;Tetraspanin-30;Tspan-30 |
HOST SPECIES |
Rabbit |
DESCRIPTION |
Anti-CD63 antibody(DMC425); IgG1 Chimeric mAb |
DELIVERY |
In Stock |
UNIPROT ID |
P08962 |
IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
CLONALITY |
Monoclonal |
REACTIVITY |
Human |
APPLICATIONS |
Flow Cyt |
RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene is a member of the transmembrane 4 superfamily; also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development; activation; growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
USAGE |
Research use only |
SKU(재고 관리 코드):DMC100425
Anti-CD63 antibody(DMC425), IgG1 Chimeric mAb
Anti-CD63 antibody(DMC425), IgG1 Chimeric mAb
PRODUCT DATA
IMAGES
Figure 1. CD63 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD63 (DMC425) on Expi293 cells transfected with human CD63 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).