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Dima Biotech

SKU(재고 관리 코드):DMC100427

Anti-GP6 antibody(DMC427), IgG1 Chimeric mAb

Anti-GP6 antibody(DMC427), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

BDPLT11; GPIV; GPVI

HOST SPECIES

Rabbit

DESCRIPTION

Anti-GP6 antibody(DMC427); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

Q9HCN6

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

USAGE

Research use only

IMAGES

antibody-DMC100427 GP6 Flow Fig1

Figure 1. Flow cytometry analysis with Anti-GP6 (DMC427) on Expi293 cells transfected with human GP6 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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