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Dima Biotech

SKU(재고 관리 코드):DMC100429

Anti-CD81 antibody(DMC429), IgG1 Chimeric mAb

Anti-CD81 antibody(DMC429), IgG1 Chimeric mAb

Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

CVID6; S5.7; TAPA1; TSPAN28

HOST SPECIES

Rabbit

DESCRIPTION

Anti-CD81 antibody(DMC429); IgG1 Chimeric mAb

DELIVERY

In Stock

UNIPROT ID

P60033

IGG TYPE

Rabbit:Human Fc chimeric IgG1

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the transmembrane 4 superfamily; also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development; activation; growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

USAGE

Research use only

IMAGES

antibody-DMC100429 CD81 Flow Fig1

Figure 1. CD81 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD81 (DMC429) on Expi293 cells transfected with human CD81 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

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