PRODUCT DATA
| TARGET | |
|---|---|
| SYNONYMS |
C5L2; GPF77; GPR77 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-GPR77 antibody(DMC482); IgG1 Chimeric mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9P296 |
| IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
Flow Cyt |
| RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors; the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway; and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Nov 2012] |
| USAGE |
Research use only |
IMAGES
Figure 1. Flow cytometry analysis with Anti-GPR77 (DMC482) on Expi293 cells transfected with human GPR77 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
