PRODUCT DATA
| TARGET | |
|---|---|
| SYNONYMS |
CD350; FZ-10; Fz10; FzE7; hFz10 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-FZD10 antibody(DMC487); IgG1 Chimeric mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9ULW2 |
| IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
Flow Cyt |
| RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis; expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq; Jul 2008] |
| USAGE |
Research use only |
IMAGES
Figure 1. Flow cytometry analysis with Anti-FZD10 (DMC487) on Expi293 cells transfected with human FZD10 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
