PRODUCT DATA
| TARGET | |
|---|---|
| SYNONYMS |
COB1; YAP; YAP2; YAP65; YKI |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-YAP1 antibody(DMC495); IgG1 Chimeric mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P46937 |
| IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
Flow Cyt |
| RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development; growth; repair; and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| USAGE |
Research use only |
IMAGES
Figure 1. Flow cytometry analysis with Anti-YAP1 (DMC495) on Expi293 cells transfected with human YAP1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
