PRODUCT DATA
| TARGET | |
|---|---|
| SYNONYMS |
ALP; ALPI; IAP; PALP; PLAP; PLAP-1 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-ALPP antibody(DMC686); IgG1 Chimeric mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P05187 |
| IGG TYPE |
Rabbit:Human Fc chimeric IgG1 |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
Flow Cyt |
| RECOMMENDED DILUTIONS |
Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is an alkaline phosphatase; a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions; which are required for its enzymatic function. One of the main sources of this enzyme is the liver; and thus; it's one of several indicators of liver injury in different clinical conditions. In pregnant women; this protein is primarily expressed in placental and endometrial tissue; however; strong ectopic expression has been detected in ovarian adenocarcinoma; serous cystadenocarcinoma; and other ovarian cancer cells. [provided by RefSeq; Aug 2020] |
| USAGE |
Research use only |
IMAGES
Figure 1. Flow cytometry analysis with Anti-ALPP(DMC686) on Expi293 cells transfected with human ALPP(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
