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Dima Biotech

SKU(재고 관리 코드):PME-M100093

Mouse CGRP Protein, hFc Tag

Mouse CGRP Protein, hFc Tag

Size
PRODUCT DATA
TARGET

SYNONYMS

CA;Ct;Ctn;Calc;Calca;CGRP1;Calc1;CGRP-1

DESCRIPTION

Recombinant mouse CGRP protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q99JA0

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

Mouse CGRP(Ser83-Phe119) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of mCGRP-hFc is approximately 25-35 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. [provided by RefSeq, Mar 2015]

USAGE

Research use only

IMAGES

sp-PME M100093 CGRP Fig.1 SDS PAGE 1
Figure 1. Mouse CGRP Protein, hFc Tag on SDS-PAGE under reducing condition.

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