| TARGET | |
|---|---|
| SYNONYMS |
GPRC5D |
| DESCRIPTION |
Human GPRC5D full length protein-synthetic nanodisc |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9NZD1 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
GPCR |
| PROTEIN PATHWAYS |
—— |
| MOLECULAR WEIGHT |
The human full length GPRC5D Protein has a MW of 38.6 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a member of the G protein-coupled receptor family. Recent studies demonstrate that GPRC5D is expressed on malignant bone marrow plasma cells, whereas normal tissue expression is limited to the hair follicle. It may represent a potential target for effector-cell–mediated therapy to treat plasma-cell disorders like MM. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):FLP100011
Human GPRC5D full length protein-synthetic nanodisc
Human GPRC5D full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were added with Flag Tag GPRC5D-Nanodisc (0.5μg/per well) on an anti-Flag monoclonal antibody pre-coated (0.5μg/per well) plate. Serial diluted anti-GPRC5D monoclonal antibody (DME100090) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-GPRC5D monoclonal antibody binding with GPRC5D-Nanodisc is 32.86ng/ml.
Figure2. Human GPRC5D-Nanodisc, Flag Tag on SDS-PAGE
