| TARGET | |
|---|---|
| SYNONYMS |
CANN6; CB-R; CNR1; CB1A; CB1K5; CB1R; CNR |
| DESCRIPTION |
Human CB1 full length protein-synthetic nanodisc |
| DELIVERY |
In Stock |
| UNIPROT ID |
P21554 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
GPCR |
| PROTEIN PATHWAYS |
Neuroactive ligand-receptor interaction |
| MOLECULAR WEIGHT |
The human full length CB1 Protein has a MW of 52.7 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):FLP100023
Human CB1 full length protein-synthetic nanodisc
Human CB1 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag CB1-Nanodisc (0.2μg/per well). Serial diluted anti-CB1 monoclonal antibody (DME100144) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CB1 monoclonal antibody binding with CB1-Nanodisc is 41.62ng/ml.
Figure2. Human CB1-Nanodisc, Flag Tag on SDS-PAGE
