| TARGET | |
|---|---|
| SYNONYMS |
IAP; MER6; OA3 |
| DESCRIPTION |
Human CD47 full length protein-synthetic nanodisc |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q08722 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
Druggable Genome, Transmembrane |
| PROTEIN PATHWAYS |
ECM-receptor interaction |
| MOLECULAR WEIGHT |
The human full length CD47 protein has a MW of 35.2 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
A membrane protein involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):FLP100039
Human CD47 full length protein-synthetic nanodisc
Human CD47 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag CD47-Nanodisc (0.2μg/per well). Serial diluted anti-CD47 monoclonal antibody (BME100050) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD47 monoclonal antibody binding with CD47-Nanodisc is 2.959ng/ml.
Figure2. Human CD47-Nanodisc, Flag Tag on SDS-PAGE
