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Dima Biotech

SKU(재고 관리 코드):FLP100039

Human CD47 full length protein-synthetic nanodisc

Human CD47 full length protein-synthetic nanodisc

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Size
PRODUCT DATA
TARGET

SYNONYMS

IAP; MER6; OA3

DESCRIPTION

Human CD47 full length protein-synthetic nanodisc

DELIVERY

In Stock

UNIPROT ID

Q08722

EXPRESSION HOST

HEK293

PROTEIN FAMILIES

Druggable Genome, Transmembrane

PROTEIN PATHWAYS

ECM-receptor interaction

MOLECULAR WEIGHT

The human full length CD47 protein has a MW of 35.2 kDa

FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0).  Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

A membrane protein involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

USAGE

Research use only

IMAGES

elisa-FLP100039 CD47 Fig.1 Elisa 1
Figure1. Elisa plates were pre-coated with Flag Tag CD47-Nanodisc (0.2μg/per well). Serial diluted anti-CD47 monoclonal antibody (BME100050) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD47 monoclonal antibody binding with CD47-Nanodisc is 2.959ng/ml.
page-FLP100039 CD47 Fig.2 SDS PAGE 1
Figure2. Human CD47-Nanodisc, Flag Tag on SDS-PAGE

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