1 1

Dima Biotech

FLP100064

Human SLC2A4 full length protein-synthetic nanodisc

Human SLC2A4 full length protein-synthetic nanodisc

Size
PRODUCT DATA
TARGET

SYNONYMS

GLUT4
DESCRIPTION

Human SLC2A4 full length protein-synthetic nanodisc
DELIVERY

3-4 weeks
UNIPROT ID

P14672
EXPRESSION HOST

HEK293
PROTEIN FAMILIES

Druggable Genome, Transmembrane
PROTEIN PATHWAYS

Adipocytokine signaling pathway, Insulin signaling pathway, Type II diabetes mellitus
MOLECULAR WEIGHT

The human full length SLC2A4 protein has a MW of 54.6 kDa
FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
USAGE

Research use only
전체 세부 정보 보기