| TARGET | |
|---|---|
| SYNONYMS |
C5L2; GPF77; GPR77 |
| DESCRIPTION |
Human GPR77 full length protein-synthetic nanodisc |
| DELIVERY |
3-4 weeks |
| UNIPROT ID |
Q9P296 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
| MOLECULAR WEIGHT |
The human full length C5AR2 protein has a MW of 36.1 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):FLP100069
Human GPR77 full length protein-synthetic nanodisc
Human GPR77 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag GPR77-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with GPR77-Nanodisc is 3.415ng/ml.
Figure2. Human GPR77-Nanodisc, Flag Tag on SDS-PAGE
